ACEI+β细胞因子阻滞剂，联用是否「1+1＞2」？

GG, Essig J, Kleinbloesem CH, Hoogkamer JFW, Wiegand UW, Wellstein A. Interactionsbetween cilazapril and propranolol in man; plasma drug concentrations, hormone and enzymeresponses, haemodynamics, agonist dose-effect curves and baroreceptor reflex. Br J ClinPharmacol (1988) 26, 547–56.[8]Belz GG, Essig J, Erb K, Breithaupt K, Hoogkamer JFW, Kneer J, Kleinbloesem CH. Pharmacokineticand pharmacodynamic interactions between the ACE inhibitor cilazapril and _x100045_-adrenoceptor antagonist propranolol in healthy subjects and in hypertensive patients. Br J ClinPharmacol (1989) 27, 317S–322S.[9]Erb KA, Essig J, Breithaupt K, Belz GG. Clinical pharmacodynamic studies with cilazapril anda combination of cilazapril and propranolol. Drugs (1991) 41 (Suppl 1) 11–17.

医学界医学小儿学频道 医学界力求其发表主旨在审核通不合时宜的精确可靠，但未曾必对已发表主旨的适时性，以及所摘录文献资料(如有)的正确性和值得注意性等重申任何允诺和尽似乎，亦不应尽因该些主旨已不合时宜、所摘录文献资料似乎的不精确或不值得注意等情况引致的任何责任。请方面各方在有别于或者以此作为决策依据时另行核查。。

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